Guadalupe Nettel (born 1973) is a Mexican writer. She was born in Mexico City and obtained a PhD in linguistics from the École des Hautes Études en Sciences Sociales in Paris. She has published in several genres, both fiction and non-fiction.

Nettel is a prolific author and a regular contributor to both Spanish- and French-language magazines, including Letras Libres, Hoja por hoja, L'atelier du roman, and L'inconvénient. In 2006 she was voted one of thirty-nine most important Latin American writers under the age of thirty-nine at the Bogotá Hay Festival.

She has lived in Montreal and Paris, and is now based in Barcelona, where she works as a translator and holds writing seminars and a workshop on Potential Literature (based on the French Oulipo). She is the author of Juegos de artificio [False Games], Les jours fossiles [Fossil Days], Pétalos y otras historias incómodas [Petals and other Awkward Stories], and El huésped [The Host], and the recipient of the Premio Herralde, third place, for El huésped, and the 2008 Premio Antonin Artaud and the 2007 Gilbert Owen Short Story Prize in Mexico for Pétalos.

Guadalupe Nettel’s stories have been described as “marvellous” by the distinguished Colombian author Juan Gabriel Vázquez, and the critic Juan Ignacio Boido has praised Nettel’s creation of “a universe where Roberto Bolaño’s visceral poets rub shoulders with the fragile but unbreakable women of Haruki Murakami.”