Dzongsar Jamyang Khyentse Rinpoche was born in Bhutan in 1961 and was recognised as the incarnation of Jamyang Khyentse Chokyi Lodro (1894-1959). From early childhood, he has studied with some of the greatest contemporary masters, particularly his father, H.H. Thinley Norbu Rinpoche and H.H. Dilgo Khyentse Rinpoche.

From a young age he has been active in preserving the Buddhist teachings, establishing centres of learning and practice, supporting practitioners, publishing books, and teaching all over the world. Dzongsar Khyentse Rinpoche supervises his traditional seat of Dzongsar Monastery and its retreat centres in Eastern Tibet, as well as his new colleges in India and Bhutan. He has also has established centres in Australia, North America, and the Far East. These are gathered under Siddhartha's Intent.

In addition to Siddhartha's Intent, in 2001, the Khyentse Foundation was founded by Dzongsar Khyentse Rinpoche. It is a non-profit organization with the stated goal "to act as a system of patronage for institutions and individuals engaged in the practice and study of Buddha's wisdom and compassion."

His two major films are The Cup (1999) and Travellers and Magicians (2003).