After a high school diploma in Visual Arts in Geneva , Léonie Bischoff left Switzerland to study in Brussels , at the École Supérieure des Arts Saint-Luc, where she obtained a degree in comics. She then moved to Paris where she published, in 2009, her first graphic story in the collection Phantasmes at Manolosanctis. With the same publisher, she participated the following year in the collective album 13m28, before publishing her first solo comic, Princess Suplex. Leonie Bischoff then returned to Brussels where she wrote and drew the graphic novel Hoodoo Darlin coming out in 2013 at Casterman. It is the first album that she signs with her full name, rather than her pseudonym "Léonie", used for her previous publications. She then worked with screenwriter Olivier Bocquet on the comic book adaptation of Camilla Läckberg's eponymous novels , La Princesse des glaces and Le Prédicateur. These albums were released in 2014 and 2015 by Casterman .

Léonie Bischoff lives and works in 2020 in Brussels and she is part of Atelier Mille with 7 other authors and cartoonists, including Thomas Gilbert , Nicolas Pitz , Jérémie Royer .

In 2020, she delivers Anaïs Nin, sur la mer des mensonges. The book is one of the five finalists for the 2021 Critics' Grand Prize, is in the selection for the Golden Fauve at the 2021 Angoulême Festival 4 and obtains the Fauve Audience Prize. The book is also selected for the 2021 Artémisia Prize for female comics.